Reviewer:
For years, vaccinating rabbits against RHDV2 came with a catch. The only USDA-approved vaccine was packaged in large multi-dose vials, which meant clinics had to gather groups of rabbits at once to use them efficiently. That setup made vaccine clinics more common—but it also made it harder for veterinarians to provide the vaccine during routine checkups or at individual appointments.
That barrier has finally shifted. Since mid 2025, single-dose vials of Medgene’s RHDV2 vaccine have been in circulation, and veterinarians across the U.S. are putting them to use. Smaller clinics that don’t see many rabbits now have more motivation to stock the vaccine, since they can use it one patient at a time without waste. This change is already making a difference, giving both general vets and exotics practices more flexibility to protect rabbits whenever care is needed.
It’s a milestone for rabbit health. RHDV2 is now endemic in the U.S., spreads easily through the environment, and kills the majority of rabbits it infects—often suddenly, with little warning. Vaccination remains the best defense.
If your rabbit hasn’t been vaccinated yet, ask your veterinarian about the single-dose rhdv2 vaccine option. This innovation makes lifesaving protection more accessible than ever.
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